Paulo Dybala scored a brace as Juventus brushed Udinese aside to reach the quarter finals of the Coppa Italia.
The Argentine combined with Higuain for the first goal of the match setting up the former the former Real Madrid man.
He then opened his account from the penalty spot on the 26th minute before adding a second with a superbly executed clip shot to make it 3-0 for Juventus three minutes shy of the hour mark.
Douglas Costa got the fourth with another spotkick after Bram Nuytinck handled in the area.
Cristiano Ronaldo withdrew from the squad earlier in the day due to illness.
The five-time Balon d’Or winner picked up a sinus infection.
Elsewhere, AC Milan beat SPAL 3-0 to book a place among the last eight. Want-away Krzysztof Piatek raced past the defence to give his team the lead after 20 minutes.
Samuel Castillejo curled in the second just before half-time, and Theo Hernandez hammered in the third in the 66th minute. Ibrahimovic did not feature in this one.
Wolves loanee scored 11 minutes into his debut to help Fiorentina beat Atalanta by 2-1.